Respiratory assessment of bronchodilator drugs.

Clinical assessment of bronchodilator drugs delivered by aerosol.

At what age do bronchodilator drugs work?

Using a modification of the forced oscillation technique we have measured respiratory resistance before and after nebulised salbutamol therapy in 32 wheezing children aged 7 months to 3 years 7 monts. 12 of the children were also studied in a total body plethysmograph. No child under 18 months of aged showed a greater than 5% fall in resistance or any fall in thoracic gas volume. In contrast, 1...

The Place of Physical Exercise and Bronchodilator Drugs in the Assessment of the Asthmatic Child.

Among the many factors that affect ventilatory function in the asthmatic subject, physical exercise and bronchodilator drugs are two of the more important. It has been shown that physical exercise has two distinct and opposite effects on ventilatory function depending upon the duration and level of exercise (Jones, Buston and Wharton, 1962). Providing the level is adequate, exercise lasting les...

Novel approach to continuous adventitious respiratory sound analysis for the assessment of bronchodilator response

BACKGROUND A thorough analysis of continuous adventitious sounds (CAS) can provide distinct and complementary information about bronchodilator response (BDR), beyond that provided by spirometry. Nevertheless, previous approaches to CAS analysis were limited by certain methodology issues. The aim of this study is to propose a new integrated approach to CAS analysis that contributes to improving ...

Emergency use of nebulised bronchodilator drugs in British hospitals.

A telephone survey was conducted to determine the emergency use of nebulised bronchodilator drugs by the registrar or senior house officer on duty for medical admissions at 67 British hospitals. All used a nebulised beta agonist (usually 5 mg salbutamol) as first line treatment for severe acute asthma or reversible obstructive lung disease. Twenty three doctors used ipratropium bromide occasion...